BBT074

Industrial Biotechnology

L-T-P3-0-0 Credits3 Session2025-26 TypeTheory
Appears in 1 semester

B.Tech Biotechnology · Sem 7 (Departmental Elective-IV)

Pre-requisites: Knowledge of Microbiology,

Syllabus

5 units · 48 lecture hours
Unit1

Unit 1: Introduction to Industrial Biotechnology

12 hrs

Introduction and scope of industrial biotechnology, historical overview of industrial fermentation processes, unit operations involved, products and market economics. Microorganisms: Isolation of industrially important microorganisms, isolation methods utilizing selection of desired characteristics, methods not utilizing selection of desired characteristics, preservation and maintenance of microorganisms, improvement of industrial microorganisms for overproduction of primary and secondary metabolites, improvement of strains by modifying properties other than the yield of products.

Unit2

Unit 2: Raw materials for fermentation process

8 hrs

Media requirements for fermentation processes, simple and complex media, medium formulation, carbon sources, nitrogen sources, minerals, vitamins and other nutrients, precursor, induces, chelator, growth factors, antifoams.

Unit3

Unit 3: Commercially important products

10 hrs

Alcohol, alcoholic beverages beer and wines etc, beneficial soil microorganisms. bio pesticides, biofertilizer, single cell proteins, baker’s yeast, high fructose corn syrup, organic acids, acetone, butanol etc., biopreservatives (Nisin), cheese, biopolymers (xanthan gum, PHB etc), Bioflavours and biopigments; microbial production of flavours and fragrances; microbial pigments in textile and food industry.

Unit4

Unit 4: Microbial production of pharmaceuticals and other bioproducts

8 hrs

Antibiotics, vitamins, enzyme and proteins, enzyme inhibitors and specialty chemicals; Transformation of nonsteroidal compounds, antibiotics, genetic engineering of microorganisms for production of nonribosomal peptides (NRPS) and polyketides (PKS), anticancer drugs.

Unit5

Unit 5: Bioreactors, Production of cell biomass and Bioenergy

10 hrs

Different type of Bioreactors and Bioreactor design, Production of ethanol, acetone, butanol, citric acid, dextran and amino acids, fuel from biomass, production and economics of biofuels, biogas, bio-refineries, Microbial Enhanced Oil Recovery (MEOR). Total lectures

Course Objectives5 points
  • To provide the knowledge of Industrial Biotechnology.
  • To understand the use of living cells such as bacteria, yeast, algae or component of cells like enzymes, plants and animals to generate industrial products and processes.
  • To study techniques for genetic improvement of micro-organisms to improve yield of bioproducts.
  • To provide the knowledge of microbial production of pharmaceuticals.
  • To provide knowledge about biofuels.
Course Outcomes (COs)5 outcomes

After completion of the course student will be able to:

  1. CO1Understand the role of industrial biotechnology in improving microbial cells as factoriesUnderstand
  2. CO2Understand the different types of bioreactors and the production aspects of commodity chemicals, pharmaceuticals and fine chemicals.Understand, Analyze
  3. CO3Apply knowledge of microorganisms in commercial production of flavours, fragrance, and microbial pigment in textile and industry.Create
  4. CO4Apply the process for commercial production of enzyme.Apply
  5. CO5Understand the concept of biofuels and the process of Microbial Enhanced Oil Recovery and Microbial Leaching.Understand, Analyze, Create

Reference Books

  1. S.No

Books

  1. YEAR OF PUBLICATION
  2. Reed G, “Prescott and Dunn’s Industrial Microbiology” CBS publishers and distributors, New Delhi (1987). , 1987
  3. P.F. Stansbury and A. Whitaker, Principles of Fermentation Technology: An Introduction to Current Concepts, Pergamon Press 1993 1993
  4. Glazer AN, Nikaido H : Microbial Biotechnology: Fundamentals of Applied Microbiology. 2007 2007
  5. Malden MA: Industrial Microbiology: An introduction; Blackwell Science 2001 2001
  6. Casida L E, “Industrial Microbiology” , New Age International Publishers Ltd. 2003
  7. Mansi E M T EL, Bryce C F A, “Fermentation Microbiology and Biotechnology”. Ane Books Publishers and Distributors 2003
  8. Shuler M L, Kargi F, “ Bioprocess Engineering- Basic Concepts” , 2nd ed, Prentice Hall of India Ltd. 2002
  9. C. Vogel and C.L. Tadaro, Fermentation and Biochemical Engineering Handbook: Principles, Process, Design and Equipment, Noyes Publications 1996
  10. Wulf Cruger and Anneliese Crueger, Biotechnology: A Textbook of Industrial Microbiology, Panima Publishing Corporation 2003
  11. Crueger W and Crueger A, “Biotechnology: A Text book of Industrial Microbiology” Sinouer Associate, Inc. Sunderland MA, USA 1990

Official AKTU syllabus

This subject is on page 11, 12 of the original AKTU PDF.

Official AKTU syllabus PDF ↗