BBI602

Artificial Intelligence and Machine Learning in Bioinformatics

L-T-P3-1-0 Credits4 Session2026-27 TypeTheory
Appears in 1 semester

B.Tech Bioinformatics · Sem 6 (Core)

Syllabus

5 units · 40 lecture hours
Unit1

Unit 1: FUNDAMENTALS OF ARTIFICIAL INTELLIGENCE

8 hrs

Introduction to Artificial Intelligence, history and evolution of AI, types of AI (Narrow, General and Super AI), intelligent agents, problem-solving approaches, knowledge representation and reasoning, search techniques (Breadth First Search, Depth First Search and A* Search).

Unit2

Unit 2: MODERN ARTIFICIAL INTELLIGENCE

8 hrs

Expert systems, Natural Language Processing (NLP), computer vision, robotics, introduction to Generative AI and Large Language Models (LLMs), AI ethics, bias, privacy and security, and emerging trends in Artificial Intelligence.

Unit3

Unit 3: FUNDAMENTALS OF MACHINE LEARNING

8 hrs

Introduction to Machine Learning, Artificial Intelligence vs Machine Learning vs Deep Learning, machine learning workflow, types of machine learning (Supervised Learning, Unsupervised Learning and Reinforcement Learning), data collection and pre-processing, feature selection, training, validation and testing datasets, overfitting and under fitting, and model evaluation using accuracy, precision, recall, F1-score and confusion matrix.

Unit4

Unit 4: SUPERVISED AND UNSUPERVISED LEARNING ALGORITHMS

8 hrs

Supervised learning algorithms: Linear Regression, Logistic Regression, Decision Tree, Random Forest, Support Vector Machine (SVM), K-Nearest Neighbour (KNN) and Naïve Bayes. Unsupervised learning algorithms: K-Means Clustering, Hierarchical Clustering and Principal Component Dr. A.P.J. Abdul Kalam Technical University, Lucknow, Uttar Pradesh Analysis (PCA). Introduction to Artificial Neural Networks (ANN) and Convolutional Neural Networks (CNN).

Unit5

Unit 5: APPLICATIONS OF ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING IN BIOINFORMATICS

8 hrs

Applications of Artificial Intelligence and Machine Learning in genomics, proteomics, transcriptomics, biological sequence analysis, disease diagnosis, drug discovery, protein structure prediction, precision medicine, medical image analysis, personalized medicine, AI-assisted clinical decision support systems, and ethical considerations in AI-based healthcare.

Course Outcomes (COs)5 outcomes

After completion of the course student will be able to:

  1. CO1Explain the fundamental concepts of Artificial Intelligence.K2
  2. CO2Describe modern AI technologies and their applications in intelligent systems and healthcare.K2
  3. CO3Apply the fundamental concepts and workflow of machine learning for data analysis and predictive modeling.K3
  4. CO4Apply supervised and unsupervised machine learning algorithms to solve classification, regression and clustering problems.K3
  5. CO5Apply AI and machine learning approaches to solve bioinformatics and healthcare problems.K3

TEXT BOOKS

  1. / REFERENCES
  2. Stuart Russell, Peter Norvig, “Artificial Intelligence: A Modern Approach”, 4th Edition, Pearson Education, 2021.
  3. Aurélien Géron, “Hands-On Machine Learning with Scikit-Learn, Keras, and TensorFlow”, 3rd Edition, O'Reilly Media, 2022.
  4. Arthur Lesk, “Introduction to Bioinformatics”, 5th Edition, Oxford University Press, 2019.
  5. David W. Mount, “Bioinformatics: Sequence and Genome Analysis”, 2nd Edition, Cold Spring Harbor Laboratory Press, 2004. Dr. A.P.J. Abdul Kalam Technical University, Lucknow, Uttar Pradesh

Official AKTU syllabus

This subject is on page 31, 32, 33 of the original AKTU PDF.

Official AKTU syllabus PDF ↗