BBI302

Applied Microbiology and Immunology

L-T-P3-1-0 Credits4 Session2025-26 TypeTheory
Appears in 1 semester

B.Tech Bioinformatics · Sem 3 (Core)

Syllabus

5 units · 40 lecture hours
Unit1

Unit 1: MICROBIAL CHARACTERISTICS AND GROWTH

8 hrs

Introduction to microbiology and microbes, morphology, structure, growth and nutrition of bacteria. Bacterial growth curve, bacterial culture methods; bacterial genetics: mutation and recombination in bacteria, plasmids, transformation, transduction and conjugation. Gram positive and Gram negative organisms, biosynthesis of bacterial cell wall.

Unit2

Unit 2: MICROBIAL ECOLOGY AND INDUSTRIAL APPLICATIONS

8 hrs

Role of microorganisms in nitrogen, biological nitrogen fixation; carbon; sulfur; and phosphorus cycles, Microbes of industrial use, Domestic and industrial sewage treatment. Food microbiology: Microbial spoilage of food products (fresh and canned), food borne infection, food preservation methods

Unit3

Unit 3: THE IMMUNE SYSTEM

8 hrs

Introduction to immune system: Innate and Adaptive immunity, Humoral and Cell mediated immune response, Cells and Molecules of the immune system, Primary and Secondary lymphoid organs, T &B cell maturation and its activation, Characteristics and types of Antigens, Haptens, adjuvants and Epitopes, Antibodies: Structure, functions and characteristics of different classes of antibodies. Monoclonal antibodies.

Unit4

Unit 4: ANTIGEN ANTIBODY INTERACTIONS

8 hrs

Antigen and antibody interactions, precipitation reactions, Serological techniques: ELISA, RIA and western blotting, Structure and Function of MHC molecules, Exogenous and Endogenous pathways of antigen processing and presentation, Overview of Complement system and cytokines, immune tolerance.

Unit5

Unit 5: IMMUNITY AND INFECTIOUS DISEASES

8 hrs

Immunity against: Bacterial disease- tuberculosis, typhoid, Protozoan disease- Malaria, Amoebiasis and Viral diseases. AIDS, Dengue, Chikungunya, Vaccine's, Hypersensitivity and Immunotherapy related threats, firewalls

Course Outcomes (COs)5 outcomes

After completion of the course student will be able to:

  1. CO1Understand fundamental basics of microbiology, growth kinetics of bacteria and bacterial geneticsK2
  2. CO2Understand the microbial ecology , application of microbes in Domestic, industry set up and and acquire knowledge of food microbiology and prevention of food spoilageK2
  3. CO3Distinguish the major cells and tissue parts of innate and adoptive immune response along with study of immunological reaction in response to different types of antigenic reactions.K2
  4. CO4Acquire basic understanding of fundamental immunological processes, Antigen antibody interaction, and MHC along with the principle and applications of immune-techniques.K3
  5. CO5Apply concepts of immunology and microbiology in disease diagnosis, and immunotherapy.K4

Text books

  1. Microbiology by Pelczar (W C Brown publication)
  2. Genral Microbiology by stainer (Mac Millan Publication)
  3. Microbiology by Pawar and Dagniwala (Himalaya publishing House).
  4. . Immunology and immunotechnology by Ashim K, Chakravarty (Oxford university Press)
  5. Immunology by C. Fatima 3. Immunology by Kuby (Free man publication)

Official AKTU syllabus

This subject is on page 5 of the original AKTU PDF.

Official AKTU syllabus PDF ↗