Unit1
Unit 1: INTRODUCTION
8 hrsHistorical aspects of Pharmacogenetics Pharmacogenomics- Biomarkers- and the promise of personalized medicine.
Syllabus
5 units · 40 lecture hoursUnit2
Unit 2: PHARMACOGENETICS
8 hrsPharmacogenetics of drug metabolism receptors- drug transporters.
Unit3
Unit 3: DRUG RESPONSE
8 hrsInter ethnic drug response- clinical viewpoints- technologies and challenges.
Unit4
Unit 4: SINGLE NUCLEOTIDE POLYMORPHISM
8 hrsIntroduction technologies for the analysis of SNPs- molecular diagnostics.
Unit5
Unit 5: SAGE
8 hrsSerial Analysis of Gene Expression (SAGE) - Principle and methodology of SAGE; applications in functional biology; use of SAGE data for mapping of disease loci.
Course Outcomes (COs)
After completion of the course student will be able to:
- CO1Understand historical aspects of pharmacogenetics, pharmacogenomics, biomarkers, and personalized medicine.K2
- CO2Apply knowledge of pharmacogenetics in drug metabolism, receptors, and transporters.K3
- CO3Explain inter-ethnic drug responses, clinical viewpoints, and related technologies.K2
- CO4Explain single nucleotide polymorphisms (SNPs) and technologies for molecular diagnostics.K2
- CO5Explain Serial Analysis of Gene Expression (SAGE) for functional biology and disease mapping.K2
TEXT BOOKS
- / REFERENCES
- Licinio J. Ma-Li Wong, “Pharmacogenomics: The Search for Individualized Therapies”, Wiley-VCH, 2002.
- Zdanowicz M, “Concepts in Pharmacogenomics”, ASHP, 2010.
- Werner Kalow, Rachel F Tyndale, Urs A Meyer, “Pharmacogenomics”, Marcel Dekker Inc., 2001.
- Adam Hedgecoe, “The Politics of Personalized Medicine- Pharmacogenetics in the Clinic”, Cambridge University Press, first edition, 2004. Dr. A.P.J. Abdul Kalam Technical University, Lucknow, Uttar Pradesh
Official AKTU syllabus
This subject is on page 23, 24 of the original AKTU PDF.